Long non-coding RNA lnc_3712 impedes nuclear reprogramming via repressing Kdm5b

Long non-coding RNA lnc_3712 impedes nuclear reprogramming via repressing Kdm5b

Long non-coding RNAs (lncRNAs) are involved in shaping chromosome conformation and regulation of preimplantation development. However, the role of lncRNA during somatic cell nuclear transfer (SCNT) reprogramming remains largely unknown. In the present study, we identified 114 upregulated lncRNAs in...

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Bibliographic Details
Main Authors: Mingtian Deng, Yongjie Wan, Baobao Chen, Xiangpeng Dai, Zifei Liu, Yingnan Yang, Yu Cai, Yanli Zhang, Feng Wang
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
somatic cell nuclear transfer
reprogramming
long non-coding RNA
Kdm5b
H3K4me3
goat
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121000512

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http://www.sciencedirect.com/science/article/pii/S2162253121000512

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