Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E2

Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E2

Acute inflammation is characterized by granulocyte infiltration followed by efferocytosing mononuclear phagocytes, which pave the way for inflammatory resolution. Until now, it was believed that resolution then leads back to homeostasis, the physiological state tissues experience before inflammation...

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Bibliographic Details
Main Authors: Justine Newson, Madhur P. Motwani, Alexandra C. Kendall, Anna Nicolaou, Giulio G. Muccioli, Mireille Alhouayek, Melanie Bennett, Rachel Van De Merwe, Sarah James, Roel P.H. De Maeyer, Derek W. Gilroy
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
macrophage
eicosanoid
autoimmunity
adaptive homeostasis
immune scarring
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312585

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717312585

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