Response to trametinib in recurrent low-grade serous ovarian cancer with NRAS mutation: A case report

Low-grade serous ovarian cancer represents a minority of ovarian cancers and has distinctive features from high grade epithelial ovarian cancer. While less aggressive, in advanced stage they can be poorly chemo-responsive and incur a treatment challenge. Next generation sequencing of tumors has allo...

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Bibliographic Details
Main Authors: Miriam Champer, Devin Miller, Dennis Yi-Shin Kuo
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Gynecologic Oncology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578919300074