Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo.

Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo.

B lymphocyte stimulator (BLyS) is a member of the TNF superfamily of cytokines. The biological activity of BLyS is mediated by three cell surface receptors: BR3/BAFF-R, TACI and BCMA. The expression of these receptors is highly restricted to B cells, both normal and malignant. A BLyS-gelonin fusion...

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Bibliographic Details
Main Authors: Troy A Luster, Ipsita Mukherjee, Jeffrey A Carrell, Yun Hee Cho, Jeffrey Gill, Lizbeth Kelly, Andy Garcia, Christopher Ward, Luke Oh, Stephen J Ullrich, Thi-Sau Migone, Robin Humphreys
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3467252?pdf=render

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http://europepmc.org/articles/PMC3467252?pdf=render

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