Incorporating immunohistochemical markers into screening methods for BRCA1-mutated breast cancer
BRCA1-mutated breast cancer (BC) is responsible for approximately 25% of hereditary breast cancer cases. BRCA1 is a tumor suppressor protein regulating the cell cycle and DNA repair; therefore its dysfunctions play a significant role in carcinogenesis. BRCA1-mutated BC is associated with basal-like...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Termedia Publishing House
2020-10-01
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Series: | Polish Journal of Pathology |
Subjects: | |
Online Access: | https://www.termedia.pl/Incorporating-immunohistochemical-markers-into-screening-methods-for-BRCA1-mutated-breast-cancer,55,42027,1,1.html |