Incorporating immunohistochemical markers into screening methods for BRCA1-mutated breast cancer

BRCA1-mutated breast cancer (BC) is responsible for approximately 25% of hereditary breast cancer cases. BRCA1 is a tumor suppressor protein regulating the cell cycle and DNA repair; therefore its dysfunctions play a significant role in carcinogenesis. BRCA1-mutated BC is associated with basal-like...

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Bibliographic Details
Main Authors: Agnieszka Tuzimek, Marta Fudalej, Aleksandra Sobiborowicz, Michał Budzik, Anna Badowska-Kozakiewicz
Format: Article
Language:English
Published: Termedia Publishing House 2020-10-01
Series:Polish Journal of Pathology
Subjects:
Online Access:https://www.termedia.pl/Incorporating-immunohistochemical-markers-into-screening-methods-for-BRCA1-mutated-breast-cancer,55,42027,1,1.html