Late Local Recurrence of Bone Giant Cell Tumors Associated with an Increased Risk for Malignant Transformation

Late Local Recurrence of Bone Giant Cell Tumors Associated with an Increased Risk for Malignant Transformation

In giant cell tumor of bone (GCTB), an intermediate malignant bone tumor, approximately 4% of all cases undergo malignant transformation. Accordingly, we analyzed risk factors for malignant transformation of GCTB treated without radiotherapy. We retrospectively reviewed medical records of 530 patien...

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Bibliographic Details
Main Authors: Shinji Tsukamoto, Alberto Righi, Andreas F. Mavrogenis, Manabu Akahane, Kanya Honoki, Yasuhito Tanaka, Davide Maria Donati, Costantino Errani
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
giant cell tumor of bone
denosumab
surgery
metastasis
malignant transformation
recurrence
Online Access:https://www.mdpi.com/2072-6694/13/14/3644

Internet

https://www.mdpi.com/2072-6694/13/14/3644

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