miR-155 effectively induces apoptosis in K562 Philadelphia positive cell line through upregulation of p27kip1

miR-155 effectively induces apoptosis in K562 Philadelphia positive cell line through upregulation of p27kip1

Introduction: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder caused by the Philadelphia chromosome translocation, at (9; 22), which results in BCR-ABL fusion tyrosine kinase oncoprotein. This fusion induces down-regulation of miR-155. Upregulation of miR-155 can influence cell f...

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Bibliographic Details
Main Authors: Mahdi Edalati Fathabad, Morteza Karimipoor, Shaban Alizadeh, Asghar Abdoli, Amir Atashi, Mahtab Sayadi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2017-06-01
Series:BioImpacts
Subjects:
Apoptosis
K562
miR-155
Philadelphia
p27kip1
Online Access:http://bi.tbzmed.ac.ir/PDF/bi-7-109.pdf

Internet

http://bi.tbzmed.ac.ir/PDF/bi-7-109.pdf

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