Impact of gene dosage on gene expression, biological processes and survival in cervical cancer: a genome-wide follow-up study.

We investigated the role of tumor copy number (CN)-altered genome (CN-AG) in the carcinogenesis of cervical cancer (CC), especially its effect on gene expression, biological processes, and patient survival. Fifty-nine human papillomavirus 16 (HPV16)-positive CCs were investigated with microarrays-31...

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Main Authors: Ingrid Medina-Martinez, Valeria Barrón, Edgar Roman-Bassaure, Eligia Juárez-Torres, Mariano Guardado-Estrada, Ana María Espinosa, Miriam Bermudez, Fernando Fernández, Carlos Venegas-Vega, Lorena Orozco, Edgar Zenteno, Susana Kofman, Jaime Berumen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4039463?pdf=render