Developmental Programming of Obesity and Liver Metabolism by Maternal Perinatal Nutrition Involves the Melanocortin System

Developmental Programming of Obesity and Liver Metabolism by Maternal Perinatal Nutrition Involves the Melanocortin System

Maternal obesity predisposes offspring to metabolic dysfunction and Non-Alcoholic Fatty Liver Disease (NAFLD). Melanocortin-4 receptor (Mc4r)-deficient mouse models exhibit obesity during adulthood. Here, we aim to determine the influence of the Mc4r gene on the liver of mice subjected to perinatal...

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Bibliographic Details
Main Authors: Paul Cordero, Jiawei Li, Vi Nguyen, Joaquim Pombo, Nuria Maicas, Marco Novelli, Paul D. Taylor, Anne-Maj Samuelsson, Manlio Vinciguerra, Jude A. Oben
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Nutrients
Subjects:
obesity
developmental programming
Non-Alcoholic Fatty Liver Disease
maternal nutrition
intra-abdominal fat
Online Access:https://www.mdpi.com/2072-6643/9/9/1041

Internet

https://www.mdpi.com/2072-6643/9/9/1041

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