Advantages and limitations of the use of optogenetic approach in studying fast-scale spike encoding.

Understanding single-neuron computations and encoding performed by spike-generation mechanisms of cortical neurons is one of the central challenges for cell electrophysiology and computational neuroscience. An established paradigm to study spike encoding in controlled conditions in vitro uses intrac...

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Bibliographic Details
Main Authors: Aleksey Malyshev, Roman Goz, Joseph J LoTurco, Maxim Volgushev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388689?pdf=render