s-dePooler: determination of polymorphism carriers from overlapping DNA pools

s-dePooler: determination of polymorphism carriers from overlapping DNA pools

Abstract Background Samples pooling is a method widely used in studies to reduce costs and labour. DNA sample pooling combined with massive parallel sequencing is a powerful tool for discovering DNA variants (polymorphisms) in large analysing populations, which is the base of such research fields as...

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Bibliographic Details
Main Authors: Aleksandr Igorevich Zhernakov, Alexey Mikhailovich Afonin, Natalia Dmitrievna Gavriliuk, Olga Mikhailovna Moiseeva, Vladimir Aleksandrovich Zhukov
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Bioinformatics
Subjects:
Sample pooling
DNA pools
Overlapping pools
Depooling
Polymorphism discovery
Online Access:http://link.springer.com/article/10.1186/s12859-019-2616-9

Internet

http://link.springer.com/article/10.1186/s12859-019-2616-9

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