Impact of Mammalian Two-Pore Channel Inhibitors on Long-Distance Electrical Signals in the Characean Macroalga <i>Nitellopsis obtusa </i>and the Early Terrestrial Liverwort <i>Marchantia polymorpha</i>
Inhibitors of human two-pore channels (TPC1 and TPC2), i.e., verapamil, tetrandrine, and NED-19, are promising medicines used in treatment of serious diseases. In the present study, the impact of these substances on action potentials (APs) and vacuolar channel activity was examined in the aquatic ch...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
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Series: | Plants |
Subjects: | |
Online Access: | https://www.mdpi.com/2223-7747/10/4/647 |