Investigating Fibroblast-Induced Collagen Gel Contraction Using a Dynamic Microscale Platform

Investigating Fibroblast-Induced Collagen Gel Contraction Using a Dynamic Microscale Platform

Mechanical forces have long been recognized as fundamental drivers in biological processes, such as embryogenesis, tissue formation and disease regulation. The collagen gel contraction (CGC) assay has served as a classic tool in the field of mechanobiology to study cell-induced contraction of extrac...

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Bibliographic Details
Main Authors: Tianzi Zhang, John H. Day, Xiaojing Su, Arthur G. Guadarrama, Nathan K. Sandbo, Stephane Esnault, Loren C. Denlinger, Erwin Berthier, Ashleigh B. Theberge
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mechanobiology
collagen gel contraction
microfluidics
dynamic
coculture
paracrine signaling
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00196/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00196/full

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