Investigating Fibroblast-Induced Collagen Gel Contraction Using a Dynamic Microscale Platform
Mechanical forces have long been recognized as fundamental drivers in biological processes, such as embryogenesis, tissue formation and disease regulation. The collagen gel contraction (CGC) assay has served as a classic tool in the field of mechanobiology to study cell-induced contraction of extrac...
Main Authors: | Tianzi Zhang, John H. Day, Xiaojing Su, Arthur G. Guadarrama, Nathan K. Sandbo, Stephane Esnault, Loren C. Denlinger, Erwin Berthier, Ashleigh B. Theberge |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-08-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2019.00196/full |
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