Screening of BRCA1 sequence variants within exon 11 by heteroduplex analysis

<p>Germ-line mutations of either BRCA1 or BRCA2 represents the major hereditary risk to breast and ovarian<br />cancer. Screening for mutations in these genes is now standard practice in molecular diagnosis, opening the way to<br />oncogenetic counselling and follow-up. Because mut...

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Bibliographic Details
Main Authors: Lucian Negura, Anca Negura
Format: Article
Language:English
Published: "Alexandru Ioan Cuza" University of Iași 2013-03-01
Series:Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
Online Access:http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/987