NAP prevents hippocampal oxidative damage in neonatal rats subjected to hypoxia-induced seizures

NAP prevents hippocampal oxidative damage in neonatal rats subjected to hypoxia-induced seizures

Neonatal seizures in which hypoxic-ischemic encephalopathy is the main triggering etiology have a challenging diagnosis and limited efficacy of treatment. NAP (NAPVSIPQ) has shown extensive neuroprotective and antioxidant capacity in vitro and in vivo. To evaluate its neuroprotective role in the con...

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Bibliographic Details
Main Authors: Samuel Greggio, Renato M. Rosa, Alexandre Dolganov, Iuri M. de Oliveira, Fernanda D. Menegat, João A.P. Henriques, Jaderson C. DaCosta
Format: Article
Language:English
Published: Elsevier 2009-12-01
Series:Neurobiology of Disease
Subjects:
Developing hippocampus
Oxidative stress
Hypoxia-induced seizures
Rodent model
NAP
Neuroprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109002277

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http://www.sciencedirect.com/science/article/pii/S0969996109002277

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