Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression

Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression

Antigen presentation on HLA molecules is a major mechanism by which the immune system monitors self and non-self-recognition. Importantly, HLA-I presentation has gained much attention through its role in eliciting anti-tumor immunity. Several determinants controlling the peptides presented on HLA ha...

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Bibliographic Details
Main Authors: Aaron Javitt, Eilon Barnea, Matthias P. Kramer, Hila Wolf-Levy, Yishai Levin, Arie Admon, Yifat Merbl
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
immunopeptidomics
cancer
proteomics
bioinformatics
inflammation
HLA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00141/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00141/full

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