Rolling-Circle Replication in Mitochondrial DNA Inheritance: Scientific Evidence and Significance from Yeast to Human Cells

Studies of mitochondrial (mt)DNA replication, which forms the basis of mitochondrial inheritance, have demonstrated that a rolling-circle replication mode exists in yeasts and human cells. In yeast, rolling-circle mtDNA replication mediated by homologous recombination is the predominant pathway for...

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Bibliographic Details
Main Authors: Feng Ling, Minoru Yoshida
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/5/514