An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans
Across metazoans, innate immunity is vital in defending organisms against viral infection. In mammals, antiviral innate immunity is orchestrated by interferon signaling, activating the STAT transcription factors downstream of the JAK kinases to induce expression of antiviral effector genes. In the n...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2017-09-01
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| Series: | mBio |
| Online Access: | http://mbio.asm.org/cgi/content/full/8/5/e00924-17 |