Formation and Function of Mammalian Epithelia: Roles for Mechanosensitive PIEZO1 Ion Channels

Mechanical forces play important roles in shaping mammalian development. In the embryo, cells experience force both during the formation of the mammalian body plan and in the ensuing phase of organogenesis. Physical forces – including fluid flow, compression, radial pressure, contraction, and osmoti...

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Bibliographic Details
Main Authors: Teneale A. Stewart, Felicity M. Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00260/full