Role of H2O2 in the oxidative effects of zinc exposure in human airway epithelial cells

Human exposure to particulate matter (PM) is a global environmental health concern. Zinc (Zn2+) is a ubiquitous respiratory toxicant that has been associated with PM health effects. However, the molecular mechanism of Zn2+ toxicity is not fully understood. H2O2 and Zn2+ have been shown to mediate s...

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Bibliographic Details
Main Authors: Phillip A. Wages, Robert Silbajoris, Adam Speen, Luisa Brighton, Andres Henriquez, Haiyan Tong, Philip A. Bromberg, Steven O. Simmons, James M. Samet
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714001116