High IFN-γ Release and Impaired Capacity of Multi-Cytokine Secretion in IGRA Supernatants Are Associated with Active Tuberculosis.

High IFN-γ Release and Impaired Capacity of Multi-Cytokine Secretion in IGRA Supernatants Are Associated with Active Tuberculosis.

Interferon gamma (IFN-γ) release assays (IGRAs) detect Mycobacterium tuberculosis (Mtb) infection regardless of the active (ATB) or latent (LTBI) forms of tuberculosis (TB). In this study, Mtb-specific T cell response against region of deletion 1 (RD1) antigens were explored by a microbead multiplex...

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Bibliographic Details
Main Authors: Séverine Carrère-Kremer, Pierre-Alain Rubbo, Amandine Pisoni, Sophie Bendriss, Grégory Marin, Marianne Peries, Karine Bolloré, Dominique Terru, Sylvain Godreuil, Arnaud Bourdin, Philippe Van de Perre, Edouard Tuaillon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5014470?pdf=render

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http://europepmc.org/articles/PMC5014470?pdf=render

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