p16 gene methylation in colorectal cancer patients with long-term follow-up Metilación de p16 en pacientes intervenidos de cáncer colorrectal tras un largo periodo de seguimiento

p16 gene methylation in colorectal cancer patients with long-term follow-up Metilación de p16 en pacientes intervenidos de cáncer colorrectal tras un largo periodo de seguimiento

Introduction: p16 gene plays an important role in the cell cycle regulation and is considered an important tumor suppressor gene. Several mechanisms of gene inactivation have been described; in this study we have focused on p16 gene promoter methylation. In colorectal cancer p16 gene methylation is...

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Bibliographic Details
Main Authors: Silvia Veganzones-de-Castro, Sara Rafael-Fernández, Marta Vidaurreta-Lázaro, Virginia de-la Orden, Beatriz Mediero-Valeros, Cristina Fernández, María Luisa Maestro-de las Casas
Format: Article
Language:English
Published: Aran Ediciones 2012-03-01
Series:Revista Espanola de Enfermedades Digestivas
Subjects:
Gen p16
Mutilación
Cáncer colorrectal
Pronóstico
p16 gene
Methylation
Colorectal cancer
Prognosis
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082012000300002

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http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082012000300002

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