Metabolic and transcriptome responses of RNAi-mediated AMPKα knockdown in Tribolium castaneum

Metabolic and transcriptome responses of RNAi-mediated AMPKα knockdown in Tribolium castaneum

Abstract Background The AMP-activated protein kinase (AMPK) is an intracellular fuel sensor for lipid and glucose metabolism. In addition to the short-term regulation of metabolic enzymes by phosphorylation, AMPK may also exert long-term effects on the transcription of downstream genes through the r...

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Bibliographic Details
Main Authors: Heng Jiang, Nan Zhang, Caihong Ji, Xiangkun Meng, Kun Qian, Yang Zheng, Jianjun Wang
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Genomics
Subjects:
Tribolium castaneum
AMPK
RNA interference
Transcriptome
Lipid metabolism
Carbohydrate metabolism IIS pathway
Online Access:http://link.springer.com/article/10.1186/s12864-020-07070-3

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http://link.springer.com/article/10.1186/s12864-020-07070-3

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