Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer’s disease animal model

Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer’s disease animal model

Harboring the behavioral and histopathological signatures of Alzheimer’s disease (AD), senescence accelerated mouse-prone 8 (SAMP8) mice are currently considered a robust model for studying AD. However, the underlying mechanisms, prioritized pathways and genes in SAMP8 mice linked to AD remain uncle...

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Bibliographic Details
Main Authors: Xiao-Rui eCheng, xiu-liang ecui, yue ezheng, gui-rong ezhang, peng eli, huang ehuang, yue-ying ezhao, wen-xia ezhou, yong-xiang ezhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Cerebral Cortex
Hippocampus
Alzheimer’s disease
Senescence accelerated mouse prone 8
Molecular network
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00065/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00065/full

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