Influence of IL10 (rs1800896) Polymorphism and TNF-α, IL-10, IL-17A, and IL-17F Serum Levels in Ankylosing Spondylitis

Influence of IL10 (rs1800896) Polymorphism and TNF-α, IL-10, IL-17A, and IL-17F Serum Levels in Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a chronic autoimmune inflammatory disease that mainly affects the axial and sacroiliac joints. Single-nucleotide polymorphisms (SNPs) in genes encoding cytokines have been associated with AS, which can interfere with the production of these cytokines and contribute to...

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Main Authors: Matheus Braga, Fernanda Formaggi Lara-Armi, Janisleya Silva Ferreira Neves, Marco Antônio Rocha-Loures, Mariana de Souza Terron-Monich, Larissa Danielle Bahls-Pinto, Quirino Alves de Lima Neto, Joana Maira Valentini Zacarias, Ana Maria Sell, Jeane Eliete Laguila Visentainer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
autoimmune disease
spondyloarthritis
rheumatological diseases
interleukin-10
interleukin-17
tumour necrosis factor alpha
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.653611/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.653611/full

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