Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library

<p>Abstract</p> <p>Background</p> <p>Casein kinase 2 (CK2) is dysregulated in various human cancers and is a promising target for cancer therapy. To date, there is no small molecular CK2 inhibitor in clinical trial yet. With the aim to identify novel CK2 inhibitors, we...

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Bibliographic Details
Main Authors: Yang Cheng-Ta, Mao Jian-Hua, Lin Yu-Ching, Xu Zhidong, Hung Ming-Szu, Chang Pey-Jium, Jablons David M, You Liang
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/135