Cyfip1 Regulates SynGAP1 at Hippocampal Synapses

Cyfip1 Regulates SynGAP1 at Hippocampal Synapses

In humans, copy number variations in CYFIP1 appear to have sweeping physiological and structural consequences in the brain, either producing or altering the severity of intellectual disability, autism, and schizophrenia. Independently, SynGAP1 haploinsufficiency produces intellectual disability and,...

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Bibliographic Details
Main Authors: Abhishek Sahasrabudhe, Fatema Begum, Christopher A. Guevara, Chenel Morrison, Kuangfu Hsiao, Nebojsa Kezunovic, Ozlem Bozdagi-Gunal, Deanna L. Benson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
CYFIP1
SynGAP
AMPA receptors
mGluR
PP2A
Rac
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2020.581714/full

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https://www.frontiersin.org/articles/10.3389/fnsyn.2020.581714/full

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