Serial Passage of <i>Cryptococcus neoformans</i> in <i>Galleria mellonella</i> Results in Increased Capsule and Intracellular Replication in Hemocytes, but Not Increased Resistance to Hydrogen Peroxide

Serial Passage of <i>Cryptococcus neoformans</i> in <i>Galleria mellonella</i> Results in Increased Capsule and Intracellular Replication in Hemocytes, but Not Increased Resistance to Hydrogen Peroxide

To gain insight into how pathogens adapt to new hosts, <i>Cryptococcus neoformans</i> (H99W) was serially passaged in <i>Galleria mellonella</i>. The phenotypic characteristics of the passaged strain (P15) and H99W were evaluated. P15 grew faster in hemolymph than H99W, in vi...

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Bibliographic Details
Main Authors: Muhammad Fariz Ali, Stephen M. Tansie, John R. Shahan, Rebecca L. Seipelt-Thiemann, Erin E. McClelland
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pathogens
Subjects:
<i>C. neoformans</i>
virulence
adaptation
<i>G. mellonella</i>
hydrogen peroxide
Online Access:https://www.mdpi.com/2076-0817/9/9/732

Internet

https://www.mdpi.com/2076-0817/9/9/732

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