Dynamic water patterns change the stability of the collapsed filter conformation of the KcsA K+ channel.

The selectivity filter of the KcsA K+ channel has two typical conformations-the conductive and the collapsed conformations, respectively. The transition from the conductive to the collapsed filter conformation can represent the process of inactivation that depends on many environmental factors. Wate...

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Bibliographic Details
Main Author: Di Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5648213?pdf=render