Gut Microbiome Influences the Efficacy of PD-1 Antibody Immunotherapy on MSS-Type Colorectal Cancer via Metabolic Pathway

Gut Microbiome Influences the Efficacy of PD-1 Antibody Immunotherapy on MSS-Type Colorectal Cancer via Metabolic Pathway

Colorectal cancer (CRC) appears to be rather refractory to checkpoint blockers except the patient with deficient in mismatch repair (dMMR). Therefore, new advances in the treatment of most mismatch repair proficiency (pMMR) (also known as microsatellite stability, MSS) type of CRC patients are consi...

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Bibliographic Details
Main Authors: Xinjian Xu, Ji Lv, Fang Guo, Jing Li, Yitao Jia, Da Jiang, Na Wang, Chao Zhang, Lingyu Kong, Yabin Liu, Yanni Zhang, Jian Lv, Zhongxin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Microbiology
Subjects:
gut microbiota
metabolic pathway
PD-1 antibody
immunotherapy
MSS-type CRC
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00814/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00814/full

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