A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction
Two-dimensional (2D) human skeletal muscle fiber cultures are ill-equipped to support the contractile properties of maturing muscle fibers. This limits their application to the study of adult human neuromuscular junction (NMJ) development, a process requiring maturation of muscle fibers in the prese...
Main Authors: | Mohsen Afshar Bakooshli, Ethan S Lippmann, Ben Mulcahy, Nisha Iyer, Christine T Nguyen, Kayee Tung, Bryan A Stewart, Hubrecht van den Dorpel, Tobias Fuehrmann, Molly Shoichet, Anne Bigot, Elena Pegoraro, Henry Ahn, Howard Ginsberg, Mei Zhen, Randolph Scott Ashton, Penney M Gilbert |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/44530 |
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