Genistein Ameliorates Scopolamine-Induced Amnesia in Mice Through the Regulation of the Cholinergic Neurotransmission, Antioxidant System and the ERK/CREB/BDNF Signaling

Genistein Ameliorates Scopolamine-Induced Amnesia in Mice Through the Regulation of the Cholinergic Neurotransmission, Antioxidant System and the ERK/CREB/BDNF Signaling

Genistein (GE) was reported to exert a wide spectrum of biological activities, including antioxidant, anti-inflammatory, anti-mutagenic, anticancer, and cardio-protective effects. In addition, both clinical and preclinical studies have recently suggested GE a potential neuroprotective and memory-enh...

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Bibliographic Details
Main Authors: Cong Lu, Yan Wang, Teng Xu, Qi Li, Donghui Wang, Lijing Zhang, Bei Fan, Fengzhong Wang, Xinmin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
genistein
scopolamine
memory deficits
cholinergic neurotransmission
antioxidant system
the ERK/CREB/BDNF signaling
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01153/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01153/full

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