Sinus node-like pacemaker mechanisms regulate ectopic pacemaker activity in the adult rat atrioventricular ring

Abstract In adult mammalian hearts, atrioventricular rings (AVRs) surround the atrial orifices of atrioventricular valves and are hotbed of ectopic activity in patients with focal atrial tachycardia. Experimental data offering mechanistic insights into initiation and maintenance of ectopic foci is l...

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Bibliographic Details
Main Authors: Sunil Jit R. J. Logantha, Sanjay R. Kharche, Yu Zhang, Andrew J. Atkinson, Guoliang Hao, Mark R. Boyett, Halina Dobrzynski
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48276-0