Loss of Human Leukocyte Antigen Class I Expression Is Associated with Poor Prognosis in Patients with Advanced Breast Cancer

Loss of Human Leukocyte Antigen Class I Expression Is Associated with Poor Prognosis in Patients with Advanced Breast Cancer

Background Human leukocyte antigen class I (HLA-I) molecules play important roles in regulating immune responses. Loss or reduction of HLA-I expression has been shown to be associated with prognosis in several cancers. Regulatory T-cells (Tregs) also play critical functions in immune response regula...

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Bibliographic Details
Main Authors: Hong Sik Park, Uiju Cho, So Young Im, Chang Young Yoo, Ji Han Jung, Young Jin Suh, Hyun Joo Choi
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2019-03-01
Series:Journal of Pathology and Translational Medicine
Subjects:
Breast neoplasms
HLA antigens
Major histocompatibility complex
Lymphocytes, tumor-infiltrating
T-lymphocytes, regulatory
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2018-10-11.pdf

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http://www.jpatholtm.org/upload/pdf/jptm-2018-10-11.pdf

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