A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives

The need for long-term treatments of chronic diseases has motivated the widespread development of long-acting parenteral formulations (LAPFs) with the aim of improving drug pharmacokinetics and therapeutic efficacy. LAPFs have been proven to extend the half-life of therapeutics, as well as to improv...

Full description

Bibliographic Details
Main Authors: Yujie Shi, An Lu, Xiangyu Wang, Zakia Belhadj, Jiancheng Wang, Qiang Zhang
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521001672