DNA Methylation Age Is More Closely Associated With Infection Risk Than Chronological Age in Kidney Transplant Recipients

DNA Methylation Age Is More Closely Associated With Infection Risk Than Chronological Age in Kidney Transplant Recipients

Background. Older kidney transplant recipients demonstrate increased rates of infection but decreased rates of rejection compared with younger recipients, suggesting that older transplant patients are functionally overimmunosuppressed. We hypothesized that this is a consequence of reduction in immun...

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Bibliographic Details
Main Authors: Joanna Schaenman, MD, PhD, Xinkai Zhou, MS, Rong Guo, MS, Maura Rossetti, PhD, Emily C. Liang, MD, Erik Lum, MD, Basmah Abdalla, MD, Suphamai Bunnapradist, MD, Phuong-Thu T. Pham, MD, Gabriel Danovitch, MD, Arun Karlamangla, MD, PhD, Elaine Reed, PhD, Steve Horvath, PhD, David Elashoff, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2020-08-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001020

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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001020

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