NADP-Dependent Aldehyde Dehydrogenase from Archaeon Pyrobaculum sp.1860: Structural and Functional Features

We present the functional and structural characterization of the first archaeal thermostable NADP-dependent aldehyde dehydrogenase AlDHPyr1147. In vitro, AlDHPyr1147 catalyzes the irreversible oxidation of short aliphatic aldehydes at 60–85°С, and the affinity of AlDHPyr1147 to the NADP+ at 60°С is...

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Main Authors: Ekaterina Yu. Bezsudnova, Tatiana E. Petrova, Natalia V. Artemova, Konstantin M. Boyko, Ivan G. Shabalin, Tatiana V. Rakitina, Konstantin M. Polyakov, Vladimir O. Popov
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Archaea
Online Access:http://dx.doi.org/10.1155/2016/9127857