Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments

Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments

Antibodies targeting Immune Checkpoints (IC) on tumor infiltrating lymphocytes improve immune responses against cancer. Recently, the expression of some ICs has also been reported on cancer cells. We used the clinically validated Ipilimumab and Nivolumab and other novel human antibodies targeting Cy...

Full description

Bibliographic Details
Main Authors: Cinzia Vetrei, Margherita Passariello, Guendalina Froechlich, Rosa Rapuano Lembo, Nicola Zambrano, Claudia De Lorenzo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
immune checkpoints
immunomodulatory mAbs
cancer immunotherapy
cardiotoxicity
irAEs
Online Access:https://www.mdpi.com/2072-6694/13/12/2858

Internet

https://www.mdpi.com/2072-6694/13/12/2858

Similar Items