Synthesis, Characterization and Biological Evaluation of New 3,5-Disubstituted-Pyrazoline Derivatives as Potential Anti-<i>Mycobacterium tuberculosis</i> H37Ra Compounds

Synthesis, Characterization and Biological Evaluation of New 3,5-Disubstituted-Pyrazoline Derivatives as Potential Anti-<i>Mycobacterium tuberculosis</i> H37Ra Compounds

A total of fourteen pyrazoline derivatives were synthesized through cyclo-condensation reactions by chalcone derivatives with different types of semicarbazide. These compounds were characterized by IR, 1D-NMR (<sup>1</sup>H, <sup>13</sup>C and Distortionless Enhancement by Po...

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Bibliographic Details
Main Authors: Kok Tong Wong, Hasnah Osman, Thaigarajan Parumasivam, Unang Supratman, Mohammad Tasyriq Che Omar, Mohamad Nurul Azmi
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
pyrazolines
<i>Mycobacterium tuberculosis</i>
antitubercular agents
molecular docking
alpha-sterol demethylase
Online Access:https://www.mdpi.com/1420-3049/26/7/2081

Internet

https://www.mdpi.com/1420-3049/26/7/2081

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