Octadecylpropyl Sulfamide Reduces Neurodegeneration and Restores the Memory Deficits Induced by Hypoxia-Ischemia in Mice

The PPAR-α agonist, oleoylethanolamide (OEA) has neuroprotective properties in stroke models. However, its rapid degradation represents a limitation for an effective therapeutic approach. In this study, we evaluated the effects of a stable OEA-modeled compound, octadecylpropyl sulfamide (SUL) on the...

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Bibliographic Details
Main Authors: Elk Kossatz, Daniel Silva-Peña, Juan Suárez, Fernando R. de Fonseca, Rafael Maldonado, Patricia Robledo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
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Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00376/full