Antibody Protection against Long-Term Memory Loss Induced by Monomeric C-Reactive Protein in a Mouse Model of Dementia

Antibody Protection against Long-Term Memory Loss Induced by Monomeric C-Reactive Protein in a Mouse Model of Dementia

Monomeric C-reactive protein (mCRP), the activated isoform of CRP, induces tissue damage in a range of inflammatory pathologies. Its detection in infarcted human brain tissue and its experimentally proven ability to promote dementia with Alzheimer’s disease (AD) traits at 4 weeks after intrahippocam...

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Bibliographic Details
Main Authors: Elisa García-Lara, Samuel Aguirre, Núria Clotet, Xenia Sawkulycz, Clara Bartra, Lidia Almenara-Fuentes, Cristina Suñol, Rubén Corpas, Peter Olah, Florin Tripon, Andrei Crauciuc, Mark Slevin, Coral Sanfeliu
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
monomeric C-reactive protein (mCRP)
biomarker
Alzheimer’s disease
mouse model of mCRP dementia
Online Access:https://www.mdpi.com/2227-9059/9/7/828

Internet

https://www.mdpi.com/2227-9059/9/7/828

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