Polymorphic regulation of mitochondrial fission and fusion modifies phenotypes of microglia in neuroinflammation

Polymorphic regulation of mitochondrial fission and fusion modifies phenotypes of microglia in neuroinflammation

Abstract Microglia are the resident macrophages of the central nervous system and play complex roles in the milieu of diseases including the primary diseases of myelin. Although mitochondria are critical for cellular functions and survival in the nervous system, alterations in and the roles of mitoc...

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Bibliographic Details
Main Authors: Mitsuhiko Katoh, Bao Wu, Huy Bang Nguyen, Truc Quynh Thai, Ryo Yamasaki, Haiyan Lu, Anna M. Rietsch, Musab M. Zorlu, Youichi Shinozaki, Yurika Saitoh, Sei Saitoh, Takashi Sakoh, Kazuhiro Ikenaka, Schuichi Koizumi, Richard M. Ransohoff, Nobuhiko Ohno
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05232-0

Internet

https://doi.org/10.1038/s41598-017-05232-0

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