Bioinformatics Identification of Anti-CRISPR Loci by Using Homology, Guilt-by-Association, and CRISPR Self-Targeting Spacer Approaches

Bioinformatics Identification of Anti-CRISPR Loci by Using Homology, Guilt-by-Association, and CRISPR Self-Targeting Spacer Approaches

As a naturally occurring adaptive immune system, CRISPR-Cas (clustered regularly interspersed short palindromic repeats–CRISPR-associated genes) systems are widely found in bacteria and archaea to defend against viruses. Since 2013, the application of various bacterial CRISPR-Cas systems has become...

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Bibliographic Details
Main Authors: Yanbin Yin, Bowen Yang, Sarah Entwistle
Format: Article
Language:English
Published: American Society for Microbiology 2019-09-01
Series:mSystems
Subjects:
aca
acr
crispr self-targeting
crispr-cas
anti-crispr
gene neighborhood
genomic island
helix-turn-helix
phage
prophage
Online Access:https://doi.org/10.1128/mSystems.00455-19

Internet

https://doi.org/10.1128/mSystems.00455-19

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