Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain.

Invasion of hepatocytes by Plasmodium sporozoites is a prerequisite for establishment of a malaria infection, and thus represents an attractive target for anti-malarial interventions. Still, the molecular mechanisms underlying sporozoite invasion are largely unknown. We have previously reported that...

Full description

Bibliographic Details
Main Authors: Samir Yalaoui, Sergine Zougbédé, Stéphanie Charrin, Olivier Silvie, Cécile Arduise, Khemais Farhati, Claude Boucheix, Dominique Mazier, Eric Rubinstein, Patrick Froissard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18389082/?tool=EBI