Physiological disturbance may contribute to neurodegeneration induced by isoflurane or sevoflurane in 14 day old rats.

BACKGROUND: Volatile anesthetics are widely used in pediatric anesthesia but their potential neurotoxicity raise significant concerns regarding sequelae after anesthesia. However, whether physiological disturbance during anesthetic exposure contributes to such side effects remains unknown. The aim o...

Full description

Bibliographic Details
Main Authors: Binbin Wu, Zipu Yu, Shan You, Yihu Zheng, Jin Liu, Yajing Gao, Han Lin, Qingquan Lian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882250?pdf=render