Preclinical models for neuroblastoma: establishing a baseline for treatment.

Preclinical models for neuroblastoma: establishing a baseline for treatment.

Preclinical models of pediatric cancers are essential for testing new chemotherapeutic combinations for clinical trials. The most widely used genetic model for preclinical testing of neuroblastoma is the TH-MYCN mouse. This neuroblastoma-prone mouse recapitulates many of the features of human neurob...

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Bibliographic Details
Main Authors: Tal Teitz, Jennifer J Stanke, Sara Federico, Cori L Bradley, Rachel Brennan, Jiakun Zhang, Melissa D Johnson, Jan Sedlacik, Madoka Inoue, Ziwei M Zhang, Sharon Frase, Jerold E Rehg, Claudia M Hillenbrand, David Finkelstein, Christopher Calabrese, Michael A Dyer, Jill M Lahti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084749?pdf=render

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http://europepmc.org/articles/PMC3084749?pdf=render

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