11β-Hydroxyandrostenedione Returns to the Steroid Arena: Biosynthesis, Metabolism and Function

The biological significance of 11β-hydroxyandrostenedione (11OHA4) has eluded researchers for the past six decades. It is now known that 11OHA4 is biosynthesized in the androgen arm of the adrenal steroidogenesis pathway and subsequently metabolized by steroidogenic enzymes in vitro, serving as prec...

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Bibliographic Details
Main Authors: Liezl M. Bloem, Karl-Heinz Storbeck, Lindie Schloms, Amanda C. Swart
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/11/13228