Identification and Targeting of Mutant Peptide Neoantigens in Cancer Immunotherapy

Identification and Targeting of Mutant Peptide Neoantigens in Cancer Immunotherapy

In recent decades, adoptive cell transfer and checkpoint blockade therapies have revolutionized immunotherapeutic approaches to cancer treatment. Advances in whole exome/genome sequencing and bioinformatic detection of tumour-specific genetic variations and the amino acid sequence alterations they i...

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Bibliographic Details
Main Authors: Daniel J. Verdon, Misty R. Jenkins
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
neoantigen
public neoantigen
private neoantigen
adoptive cell transfer
immunotherapy
tumour-infiltrating lymphocytes
Online Access:https://www.mdpi.com/2072-6694/13/16/4245

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https://www.mdpi.com/2072-6694/13/16/4245

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