DEVELOPMENT AND VALIDATION OF A SPECTROFLUORIMETRIC METHOD FOR THE DETERMINATION OF PHENIBUT IN TABLET DRUGS

The developed method for the quantitative determination of phenibut in tablet drugs is based on the dansylation reaction in an alkaline medium (pH 9.18). The reaction results in the formation of a fluorescent derivative with λem=505 nm and λex=335 nm. Optimal conditions were selected to complete the...

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Bibliographic Details
Main Authors: O. I. Lazovskaya, V. N. Leontiev, E. V. Litvinova
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/504